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THE GROWTH OF HOMOGENEOUS EMBRYO TOOTH BUD TRANSPLANTED INTO THE ALVEOLAR SOCKET OF A RAT

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À弮ö, Á¤ÇѼº, ÀÌÁ¦È£, ±è¼º¿À, ÃÖº´Àç,
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À弮ö ( Chang Suk-Chul ) - ¿¬¼¼´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç
Á¤ÇѼº ( Jung Han-Sung ) - ¿¬¼¼´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­»ý¹°Çб³½Ç
ÀÌÁ¦È£ ( Lee Jae-Ho ) - ¿¬¼¼´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç
±è¼º¿À ( Kim Seong-Oh ) - ¿¬¼¼´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç
ÃÖº´Àç ( Choi Byung-Jai ) - ¿¬¼¼´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç

Abstract

Á¤»óÀûÀÎ Ä¡¿­ÀÇ Çü¼º ¹× Ä¡¾ÆÀÇ »ý¼º°úÁ¤À» ºÐ¼®ÇÏ°í ½ÇÁ¦·Î ÀÓ»ó¿¡ Àû¿ëÇϱâ À§ÇØ Ä¡¾ÆÀÇ ¹ß»ý°úÁ¤À» ¿¬±¸ÇÏ´Â °ÍÀº ¸Å¿ì Áß¿äÇÏ´Ù.

º» ¿¬±¸´Â ÀÌ½ÄµÈ ÅÂ¾Æ Ä¡¾Æ½ÏÀÇ ¼®È¸È­°¡ °¡´ÉÇÏ°í Á¤»óÀûÀÎ ±¸Á¶·Î ¹ßÀ°ÇÒ ¼ö ÀÖ´ÂÁö ¹àÈ÷±â À§ÇØ, ±×¸®°í ¾Ç°ñ ÀÚü°¡ »õ·Î¿î ÀÌ½Ä °ø¿©ºÎ·Î »ç¿ë°¡´ÉÇÑÁö ¾Ë±â À§ÇØ ÈòÁãÀÇ ¹ßÄ¡¿Í¿¡ Ä¡¾Æ½ÏÀ» À̽ÄÇÏ¿© Ä¡¾ÆÀÇ Çü¼ºÀ» »ìÆ캸°íÀÚ ÇÏ¿´´Ù. À̸¦ À§ÇÏ¿© ¼º¼÷ÇÑ ÈòÁãÀÇ »ó¾Ç Á¦ 1±¸Ä¡¸¦ ¹ß°ÅÇÑ ¹ßÄ¡¿Í¿¡ 13.5ÀÏµÈ Å¾ÆÁãÀÇ Ä¡¾Æ½ÏÀ» À̽ÄÇÑ ÈÄ 4,8ÁÖ ÈÄ¿¡ Èñ»ýÇÏ¿© Á¶Á÷ÇÐÀû ¹× ¹æ»ç¼±ÇÐÀûÀ¸·Î °üÂûÇÏ¿© ´ÙÀ½°ú °°Àº °á°ú¸¦ ¾ò¾ú´Ù.

1. ÀÌ½ÄµÈ Ä¡¾Æ½Ï¿¡¼­ »ó¾ÆÁú°ú ¹é¾ÇÁú, Ä¡¼ö, Ä¡ÁÖÀδëÀÇ ¼Ò°ßÀ» °®´Â ¼®È¸È­µÈ Á¶Á÷ÀÌ Çü¼ºµÇ¾ú´Ù.

2. Çü¼ºµÈ °æÁ¶Á÷ ¹× ¿¬Á¶Á÷Àº Á¤»óÀûÀÎ Ä¡¾ÆÇü¼º°úÁ¤¿¡ ºñÇØ ¹ßÀ°ÀÌ ´Ê¾úÀ¸¸ç À¯Âø ¹× °ñ¾ç»ó¾ÆÁú(osteodentin)°ú °°Àº ºñÁ¤»óÀû Á¶Á÷ÀÌ °üÂûµÇ¾ú´Ù.

3. ¼®È¸È­µÈ Á¶Á÷Àº 8ÁÖ³»¿¡ ¾Ç±ÃÀ¸·Î ¸ÍÃâÇÏ´Â ¼Ò°ßÀÌ °üÂûµÇÁö ¾Ê¾Ò´Ù.

The developmental process of a tooth is being presented as an important study subject to analyze formation of normal dental arch and tooth.

The purpose of this study was to see the formation of tooth from a tooth bud transplanted in a white rat regarding that the jawbone could be used as a new donor site of a trasplant. The first molar of a matured white rat was extracted and the tooth bud of a 13.5 day rat embryo was transplanted. The histological and radiographical results after 4 and 8 weeks respectively are as the following.

1. Calcification in dentin, cementum, pulp and periodontal ligament was formed from the tooth bud transplanted in the alveolar socket.

2. The development of hard and soft tissue was delayed compared to the normal tooth formation and abnormal histologic features such as ankylosis and osteodentin were found.

3. The formed hard tissue did not erupt into the jaw within 8 weeks.

Å°¿öµå

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Jawbone;Tooth bud;Transplant;Tooth formation;Alveolar socket

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